CELLINK and Nanoscribe Announce New Jointly Developed Quantum X Bio 3D Printer

3D printer manufacturers CELLINK and Nanoscribe, sister companies under the BICO banner, have announced their new jointly developed Quantum X bio 3D printing system.

The machine combines CELLINK’s bioprinting capabilities with Nanoscribe’s two-photon polymerization (2PP) technology and is marketed as the “world’s most accurate 3D bioprinter”.

With its sub-micron resolution printing capabilities, the Quantum X bio is ultimately destined to miniaturize bio-printing. CELLINK and Nanoscribe have directed their latest system towards research institutes and R&D teams looking for advanced biomedical applications such as tissue engineering and regenerative medicine.

“Co-development of products like this is the exact reason we are so proud to be part of the BICO Group,” says Cecilia Edobo, CEO of CELLINK. “We look forward to delivering this system to our customers and witnessing the wonderful breakthroughs they will achieve. “

The Quantum X bio 3D printer. Photo via BICO.

United under BICO

BICO, the parent company of CELLINK and Nanoscribe, describes itself as a bioconvergence company. By combining cutting-edge technologies such as 3D bioprinting, AI and robotics, the company aims to enable a wide variety of biomedical applications for tissue engineering, drug development and regenerative medicine. Through its subsidiary CELLINK, BICO’s bio-printers, bio-inks, software and services are used by more than 1,000 academic, pharmaceutical and industrial laboratories around the world.

Since the rebranding in August 2021, BICO has obtained two new patents for 3D bioprinting of temperature sensitive bioinks. The company’s achievements are ultimately designed to enable higher cell viability and improved reproducibility with bio-inks such as collagen and gelatin, accelerating R&D applications.

More recently, the company also signed a $ 1.5 million manufacturing contract with regenerative joint replacement startup Nanochon. The deal will see Nanochon purchase $ 1.5 million worth of products and services from BICO’s SCIENION company to develop its 3D-printed regenerative joint implants, which the start-up claims will lead to faster recovery. patients while reducing costs for healthcare providers.

Founded in 2007, Nanoscribe is one of the most recent additions to the BICO family, having been acquired for 50 million euros in May 2021. The company’s product portfolio includes the Quantum X 3D printer, the Quantum form X and several nanoprinting resins.

Martin Hermatschweiler, CEO of Nanoscribe, said: “Our industry-proven two-photon polymerization technology, combined with CELLINK’s bio-printing expertise, will be a game-changer for many challenging biological and biomedical applications, and we are looking forward to expanding our 3D Microfabrication Station in Life Sciences with a dedicated bioprinter.

Micro-samples 3D printed by Nanoscribe.  Image via Nanoscribe.
Micro-samples 3D printed by Nanoscribe. Image via Nanoscribe.

The Quantum X bio 3D printer

The upcoming Quantum X bio 3D printer is based on Nanoscribe’s established Quantum X platform. Running on a customized version of the company’s 2PP technology, the system has been adapted for bioprinting applications. With the help of CELLINK bioprinting experts, the partners integrated features such as precise temperature control, a sterile environment and compatibility with functionalized biomaterials.

Like its 2PP predecessors, the Quantum X bio is capable of printing resolutions up to just 100 nanometers. This level of detail in bio-manufacturing is expected to accelerate innovation in areas such as tissue engineering, smart hydrogel materials, drug delivery, mechanobiology, and vascularized tissue.

According to BICO, the new 3D bio-printer will allow users to fabricate custom scaffolds for cell studies, microfluidic elements, microneedle arrays and even microrobots.

Hermatschweiler adds: “The launch of Quantum X bio confirms the power of collaboration within the BICO Group, and we are delighted to unleash the full potential of the fusion of technical disciplines and life sciences.

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The image shown shows the Quantum X bio 3D printer. Photo via BICO.

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